54 Results for "

Gelsemium eleganis (Gardn. et Champ.) Benth.

" in MedChemExpress (MCE) Product Catalog:
Products (54)

54 Results for "Gelsemium eleganis (Gardn. et Champ.) Benth." in MCE Product Catalog:

8
Dihydrokaempferol
Dihydrokaempferol
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8 Publications Verification
Art. -Nr.: HY-N2897
CAS. Nr.: 480-20-6
Category:  

Flavanonols Flavonoids Leguminosae Phenols Polyphenols Bauhinia championii (Benth.) Benth. Plants Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis Bcl-2 Family

Dihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic agents .
7
Tectorigenin
Tectorigenin
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7 Cited Publications
Art. -Nr.: HY-N0792
CAS. Nr.: 548-77-6
Category:  

Flavonoids Leguminosae Pueraria lobate (Willd.) Ohwi Plants Disease Research Fields Inflammation/Immunology Cancer Isoflavones

Target:  

Others

Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria lobate Benth.
Gelsemine
Gelsemine
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Art. -Nr.: HY-N0388
CAS. Nr.: 509-15-9
Category:  

Alkaloids Pyrrole Alkaloids Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth.

Target:  

Others

Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects.
Koumine
Koumine
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Art. -Nr.: HY-N1440
CAS. Nr.: 1358-76-5
Category:  

Alkaloids Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Disease Research Fields Inflammation/Immunology Indole Alkaloids

Target:  

Bcl-2 Family

Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells . Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities , protects against the development of arthritis in Rheumatoid arthritis (RA) animal models .
Humantenine
Humantenine
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Art. -Nr.: HY-N4031
CAS. Nr.: 82375-29-9
Category:  

Alkaloids Other Diseases Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Disease Research Fields Indole Alkaloids

Target:  

Anaplastic lymphoma kinase (ALK) METTL3

Humantenine is a highly toxic indole alkaloid from Gelsemium elegans (Gardn. & Champ.) Benth. that binds to RNA m6A modification regulatory proteins (ALKBH5, METTL). Humantenine stably binds via hydrogen bonding and hydrophobic interactions and disrupts the m6A methylation level of target genes, thereby impairing the expression of intestinal epithelial cell tight junction and cytoskeleton-related genes, causing intestinal barrier dysfunction and significant intestinal cytotoxicity. The intraperitoneal injection LD50 values of Humantenine are <1 mg/kg in mice, 1.2 mg/kg in male rats and 1.5 mg/kg in female rats, respectively. Species differences exist in the metabolism of Humantenine in human, porcine, goat and rat liver microsomes, and demethylation, dehydrogenation and oxidation occur in liver microsomes .
Androsin
Androsin
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Art. -Nr.: HY-N1399
CAS. Nr.: 531-28-2
Category:  

Ketones, Aldehydes, Acids Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Disease Research Fields Inflammation/Immunology

Target:  

AMPK PI3K Autophagy

Androsin is an active compound isolated from Picrorhiza Kurroa Royle ex Benth. Androsin activates AMPKα/PI3K/Beclin1/LC3 signaling pathway, inhibits SREBP1c/FASN signaling pathway. Androsin can be used in research of asthma and non-alcoholic fatty liver disease (NAFLD). Androsin is orally active .
Buddlejasaponin IVb
Buddlejasaponin IVb
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Art. -Nr.: HY-N2138
CAS. Nr.: 152580-79-5
Category:  

Triterpenes Prosopis juliflora (Sw.) DC. Labiatae Dipsacaceae Terpenoids Dipsacus asper Wall. Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

Buddlejasaponin IVb (Compound 2), a triterpene saponin isolated from Clinopodium chinense (Benth.) O. Kuntze, Compound 2 has hemostasis efficacy, shortens thrombin time (TT) by 20.6 % .
Frangulin A
Frangulin A
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Art. -Nr.: HY-N8344
CAS. Nr.: 521-62-0
Category:  

Ventilago leiocarpa Benth. Quinones Anthraquinones Plants Rhamnaceae

Target:  

Others

Frangulin A is a emodin derivative. Frangulin A can be obtained from Ventilago leiocarpa Benth .
Thaumatins
Thaumatins
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Art. -Nr.: HY-W540600
CAS. Nr.: 53850-34-3
Category:  

Marantaceae Thaumatococcus daniellii (Benn.) Benth. Natural Products Other Diseases Plants Disease Research Fields Sweeteners Food Research

Target:  

Environmental Pollutants

Thaumatins is a protein, which can be purified from the fruit of Thaumatococcus daniellii Benth. Thaumatins is 100,000 times sweeter than sucrose on a molar basis .
(Z)-Akuammidine
(Z)-Akuammidine
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Art. -Nr.: HY-N0969
CAS. Nr.: 113973-31-2
Synonyms: 19-(Z)-Akuammidine; (Z)-Rhazine
Category:  

Natural Products Other Diseases Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Disease Research Fields

Target:  

Others

(Z)-Akuammidine ((Z)-Rhazine) is isolated from Gelsemium elegans .
Millepachine
Millepachine
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Art. -Nr.: HY-N7591
CAS. Nr.: 1393922-01-4
Category:  

Flavonoids Chalcones Leguminosae Millettia pachycarpa Benth. Plants Disease Research Fields Cancer

Target:  

Apoptosis

Millepachine is a bioactive natural chalcone from Chinese herbal medicine Millettia pachycarpa Benth, exhibits strong antitumor effects against numerous human cancer cells both in vitro and in vivo .
Gelsempervine A
Gelsempervine A
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Art. -Nr.: HY-N3939
CAS. Nr.: 865187-17-3
Synonyms: 16-epi-Nb-Methylvoacarpine
Category:  

Alkaloids Pyridine Alkaloids Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth.

Target:  

Others

Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans .
N-2-Cyclohexylethyl-N-methylamine
N-2-Cyclohexylethyl-N-methylamine
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Art. -Nr.: HY-W193398
CAS. Nr.: 62141-38-2
Target:  

Monoamine Oxidase

Forschungsgebiete:  

Cardiovascular Disease

N-2-Cyclohexylethyl-N-methylamine is an amine from A.ridigula Benth for a reduction of monoamine oxidase (MAO) activity .
2-Hydroxy-1-methoxyanthraquinone
2-Hydroxy-1-methoxyanthraquinone
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Art. -Nr.: HY-N5125
CAS. Nr.: 6170-06-5
Category:  

Quinones other families Monophenols Anthraquinones Phenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Bacterial

2-Hydroxy-1-methoxyanthraquinone could be isolated from the stem bark of Morinda lucida Benth. (Rubiaceae) and possesses antibacterial activity .
Rehmannioside B
Rehmannioside B
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Art. -Nr.: HY-N10694
CAS. Nr.: 81720-06-1
Category:  

Plantaginaceae Iridoids Terpenoids Picrorhiza kurroa Royle ex Benth. Plants

Target:  

Others

Rehmannioside B is a desacyl derivative of Picrorhizaoside B, which can be isolated from the methanol extract of the rhizomes of Picrorhiza kurroa Royle ex Benth. (Plantaginaceae) .
Tectorigenin (Standard)
Tectorigenin (Standard)
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Art. -Nr.: HY-N0792R
CAS. Nr.: 548-77-6
Category:  

Flavonoids Leguminosae Pueraria lobate (Willd.) Ohwi Plants Isoflavones

Target:  

Reference Standards Others

Tectorigenin (Standard) is the analytical standard of Tectorigenin. This product is intended for research and analytical applications. Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria lobate Benth.
Digitolutein
Digitolutein
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Art. -Nr.: HY-121211
CAS. Nr.: 477-86-1
Reinheit:  94.99%
Category:  

Morinda lucida Benth. Rubiaceae Plants

Target:  

Parasite

Digitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of Plasmodium falciparum with an IC50 value of 12.92 μg/mL. Digitolutein can be used for the research of infection .
Gelsevirine
Gelsevirine
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Art. -Nr.: HY-N3940
CAS. Nr.: 38990-03-3
Category:  

Alkaloids Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Indole Alkaloids

Target:  

Others

Gelsevirine is the major alkaloid in Gelsemium elegans with potent anxiolytic effects. The anxiolytic mechanism of Gelsevirine may be involved in the agonist action of the glycine receptor in the brain. Gelsevirine has anti-proliferation activity with IC50 values of 1.41 mM and 1.22 mM for SW480 cells and MGC80-3 cells, respectively .
11-Hydroxyrankinidine
11-Hydroxyrankinidine
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Art. -Nr.: HY-N1020
CAS. Nr.: 122590-03-8
Target:  

Others

Forschungsgebiete:  

Others

11-Hydroxyrankinidine is an alkaloid compound isolated from the whole plant of Gelsemium elegans .
Sempervirine nitrate
Sempervirine nitrate
0 Images
Art. -Nr.: HY-N7507A
CAS. Nr.: 17994-15-9
Target:  

Wnt β-catenin

Forschungsgebiete:  

Cancer

Sempervirine is an alkaloid derived from Gelsemium elegans Benth.. Sempervirine inhibits the proliferation of hepatocellular carcinoma (HCC) cells and induces apoptosis by regulating Wnt/β-catenin pathway .
Assay Types