57 Results for "

Gelsemium eleganis (Gardn. et Champ.) Benth.

" in MedChemExpress (MCE) Product Catalog:
Products (57)

57 Results for "Gelsemium eleganis (Gardn. et Champ.) Benth." in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-N2897
CAS No.: 480-20-6
Dihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic agents .
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-N0792
CAS No.: 548-77-6
Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria lobate Benth.
loading...
    loading...
Cat. No.: HY-N0388
CAS No.: 509-15-9
Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects.
loading...
    loading...
Cat. No.: HY-N1440
CAS No.: 1358-76-5
Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells . Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities , protects against the development of arthritis in Rheumatoid arthritis (RA) animal models .
loading...
    loading...
Cat. No.: HY-N4031
CAS No.: 82375-29-9
Humantenine is a highly toxic indole alkaloid from Gelsemium elegans (Gardn. & Champ.) Benth. that binds to RNA m6A modification regulatory proteins (ALKBH5, METTL). Humantenine stably binds via hydrogen bonding and hydrophobic interactions and disrupts the m6A methylation level of target genes, thereby impairing the expression of intestinal epithelial cell tight junction and cytoskeleton-related genes, causing intestinal barrier dysfunction and significant intestinal cytotoxicity. The intraperitoneal injection LD50 values of Humantenine are <1 mg/kg in mice, 1.2 mg/kg in male rats and 1.5 mg/kg in female rats, respectively. Species differences exist in the metabolism of Humantenine in human, porcine, goat and rat liver microsomes, and demethylation, dehydrogenation and oxidation occur in liver microsomes .
loading...
    loading...
Cat. No.: HY-N1399
CAS No.: 531-28-2
Androsin is an active compound isolated from Picrorhiza Kurroa Royle ex Benth. Androsin activates AMPKα/PI3K/Beclin1/LC3 signaling pathway, inhibits SREBP1c/FASN signaling pathway. Androsin can be used in research of asthma and non-alcoholic fatty liver disease (NAFLD). Androsin is orally active .
loading...
    loading...
Cat. No.: HY-N2138
CAS No.: 152580-79-5
Buddlejasaponin IVb (Compound 2), a triterpene saponin isolated from Clinopodium chinense (Benth.) O. Kuntze, Compound 2 has hemostasis efficacy, shortens thrombin time (TT) by 20.6 % .
loading...
    loading...
Cat. No.: HY-N8344
CAS No.: 521-62-0
Frangulin A is a emodin derivative. Frangulin A can be obtained from Ventilago leiocarpa Benth .
loading...
    loading...
Cat. No.: HY-W540600
CAS No.: 53850-34-3
Thaumatins is a protein, which can be purified from the fruit of Thaumatococcus daniellii Benth. Thaumatins is 100,000 times sweeter than sucrose on a molar basis .
loading...
    loading...
Cat. No.: HY-N0969
CAS No.: 113973-31-2
Synonyms: 19-(Z)-Akuammidine; (Z)-Rhazine
(Z)-Akuammidine ((Z)-Rhazine) is isolated from Gelsemium elegans .
loading...
    loading...
Cat. No.: HY-N7591
CAS No.: 1393922-01-4
Millepachine is a bioactive natural chalcone from Chinese herbal medicine Millettia pachycarpa Benth, exhibits strong antitumor effects against numerous human cancer cells both in vitro and in vivo .
loading...
    loading...
Cat. No.: HY-N3939
CAS No.: 865187-17-3
Synonyms: 16-epi-Nb-Methylvoacarpine
Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans .
loading...
    loading...
Cat. No.: HY-W193398
CAS No.: 62141-38-2
Target:  

Monoamine Oxidase

Research Areas:  

Cardiovascular Disease

N-2-Cyclohexylethyl-N-methylamine is an amine from A.ridigula Benth for a reduction of monoamine oxidase (MAO) activity .
loading...
    loading...
Cat. No.: HY-N5125
CAS No.: 6170-06-5
2-Hydroxy-1-methoxyanthraquinone could be isolated from the stem bark of Morinda lucida Benth. (Rubiaceae) and possesses antibacterial activity .
loading...
    loading...
Cat. No.: HY-N10694
CAS No.: 81720-06-1
Rehmannioside B is a desacyl derivative of Picrorhizaoside B, which can be isolated from the methanol extract of the rhizomes of Picrorhiza kurroa Royle ex Benth. (Plantaginaceae) .
loading...
    loading...
Cat. No.: HY-N0792R
CAS No.: 548-77-6
Tectorigenin (Standard) is the analytical standard of Tectorigenin. This product is intended for research and analytical applications. Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria lobate Benth.
loading...
    loading...
Cat. No.: HY-121211
CAS No.: 477-86-1
Purity:  94.99%
Target:  

Parasite

Digitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of Plasmodium falciparum with an IC50 value of 12.92 μg/mL. Digitolutein can be used for the research of infection .
loading...
    loading...
Cat. No.: HY-N3940
CAS No.: 38990-03-3
Gelsevirine is the major alkaloid in Gelsemium elegans with potent anxiolytic effects. The anxiolytic mechanism of Gelsevirine may be involved in the agonist action of the glycine receptor in the brain. Gelsevirine has anti-proliferation activity with IC50 values of 1.41 mM and 1.22 mM for SW480 cells and MGC80-3 cells, respectively .
loading...
    loading...
Cat. No.: HY-N1020
CAS No.: 122590-03-8
Target:  

Others

Research Areas:  

Others

11-Hydroxyrankinidine is an alkaloid compound isolated from the whole plant of Gelsemium elegans .
loading...
    loading...
Cat. No.: HY-N7507A
CAS No.: 17994-15-9
Target:  

Wnt β-catenin

Research Areas:  

Cancer

Sempervirine is an alkaloid derived from Gelsemium elegans Benth.. Sempervirine inhibits the proliferation of hepatocellular carcinoma (HCC) cells and induces apoptosis by regulating Wnt/β-catenin pathway .
loading...
    loading...